Antiemetic use during pregnancy and child neurodevelopment: population-based birth cohort study
This large-scale study found no association between antiemetic exposure during pregnancy and the risk of neurodevelopmental disorders or delays in children, providing reassurance for the use of antiemetics in pregnancy to treat nausea and vomiting. However, the slightly elevated risks observed in certain subgroups warrant further investigation. Meanwhile, these findings may assist in guiding decisions when considering antiemetic treatment during pregnancy.
Authors
- Ju‐Young Shin (ORCID: https://orcid.org/0000-0003-1010-7525)
- Jung Yeol Han (ORCID: https://orcid.org/0000-0001-5611-2392)
- Young June Choe (ORCID: https://orcid.org/0000-0003-2733-0715)
- Eun‐Young Choi (ORCID: https://orcid.org/0000-0003-4208-791X)
- Yongtai Cho (ORCID: https://orcid.org/0000-0003-3303-7881)
- Hoon Kim (ORCID: https://orcid.org/0000-0002-5623-6368)
Institutions
- Seoul National University (KR)
- Samsung (South Korea) (KR)
- Korea University Medical Center (KR)
- Seoul National University Hospital (KR)
- Karolinska Institutet (SE)
- Inje University Ilsan Paik Hospital (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1186/s12916-025-04497-x
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea