Long-Term Cognitive and Language Outcomes at the Age of Seven Following Arterial Presumed Perinatal Ischemic Stroke: A Case Report

The brain in healthy adults shows language localization in the left hemisphere, and the evidence from the literature supports neural plasticity after traumatic injuries. What happens if an injury occurs early in brain development? How does early unilateral brain damage affect a child's ability to acquire language? Evidence regarding language development after early unilateral brain damage is mixed. Therefore, this case report aims to present the language and cognitive status at the age of seven in a child who suffered a left-sided arterial presumed perinatal ischemic stroke (APPIS), with reference to her MRI findings. As part of her ongoing rehabilitation, she has received continuous speech therapy since age four and physiotherapy since six months of age. The current evaluation provides insights into long-term neurodevelopmental outcomes following early brain injury, highlighting the variability in clinical outcomes and considering the potential for functional restitution.

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Journal
Brain Sciences
Published
2025-11-29
DOI
https://doi.org/10.3390/brainsci15121291
Primary Topic
Neonatal and fetal brain pathology
Type
article
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article

Long-Term Cognitive and Language Outcomes at the Age of Seven Following Arterial Presumed Perinatal Ischemic Stroke: A Case Report

Maša Marisavljević, Mile Vuković, Nenad Polomac, Ivana Bogavac et al.
Brain Sciences
Neonatal and fetal brain pathology
article

Long-Term Cognitive and Language Outcomes at the Age of Seven Following Arterial Presumed Perinatal Ischemic Stroke: A Case Report

Maša Marisavljević, Mile Vuković, Nenad Polomac, Ivana Bogavac, Ljiljana Jeličić, Jelena Djordjević, Ivana Pavković
article en

Abstract

The brain in healthy adults shows language localization in the left hemisphere, and the evidence from the literature supports neural plasticity after traumatic injuries. What happens if an injury occurs early in brain development? How does early unilateral brain damage affect a child's ability to acquire language? Evidence regarding language development after early unilateral brain damage is mixed. Therefore, this case report aims to present the language and cognitive status at the age of seven in a child who suffered a left-sided arterial presumed perinatal ischemic stroke (APPIS), with reference to her MRI findings. As part of her ongoing rehabilitation, she has received continuous speech therapy since age four and physiotherapy since six months of age. The current evaluation provides insights into long-term neurodevelopmental outcomes following early brain injury, highlighting the variability in clinical outcomes and considering the potential for functional restitution.

Brain SciencesVol. 15(12)
Goethe University Frankfurt (DE), University of Kragujevac (RS), University of Belgrade (RS), University Hospital Frankfurt (DE)
Openalex Percentile: Top 52%
Neonatal and fetal brain pathology
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Long-Term Cognitive and Language Outcomes at the Age of Seven Following Arterial Presumed Perinatal Ischemic Stroke: A Case Report — Maša Marisavljević, Mile Vuković, et al. · Brain Sciences (2025) | TGRS Research Map | TGRS