Sex Differences in the Association Between Inflammatory Biomarkers (Hs-CRP, IL-6, IL-10, TNF-α) and Frailty in Hospitalized Adults Aged ≥65 in Taizhou, China: A Cross-Sectional Study
In older adults, elevated levels of hs-CRP, IL-6, and IL-10 are associated with higher frailty risk; the associations are significantly stronger in women than in men. These findings emphasize considering sex differences in frailty management; however, longitudinal studies are required to confirm causality.
Authors
- Heng Yang (ORCID: https://orcid.org/0000-0002-1491-4490)
- Weihong Zhang (ORCID: https://orcid.org/0000-0002-2603-1820)
- Huiping Mao (ORCID: https://orcid.org/0009-0007-0286-9315)
- Dan Xu (ORCID: https://orcid.org/0000-0002-6593-4109)
- Xiaoyu Liu (ORCID: https://orcid.org/0000-0003-3773-8554)
- Jiechenming Xiao
Institutions
- Taizhou First People's Hospital (CN)
Publication Details
- Journal
- Clinical Interventions in Aging
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/cia.s553964
- Citations
- 2
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 2.45
Funders
- Taizhou University