The U-Shaped Association Between Remnant Cholesterol and Postoperative Survival in Hepatocellular Carcinoma: Development and Validation of an Interpretable Machine Learning Model

RC demonstrates a novel U-shaped association with HCC postoperative survival in an Asian HBV-endemic cohort, underscoring its role as a significant biomarker reflecting metabolic imbalance. The developed machine learning model, which integrates RC, provides accurate, interpretable, and individualized risk assessment, offering a valuable tool for clinical prognostication and potential guidance for personalized management strategies.