Untangling the prognostic value of diastolic dysfunction, NT-proBNP, and frailty in older patients with preserved left ventricular ejection fraction without valvular disease
Compared to NT-proBNP and frailty, DD offers limited added value in risk stratification for older people with preserved ejection fraction and no valvular disease. Frailty emerged as the strongest and most consistent predictor of mortality and hospitalization, and was central in the all-cause mortality and hospitalization decision-tree models.
Authors
- Anne–Catherine Pouleur (ORCID: https://orcid.org/0000-0002-2395-1787)
- Agnès Pasquet (ORCID: https://orcid.org/0000-0002-3778-6604)
- Benoît Boland (ORCID: https://orcid.org/0000-0002-5857-3085)
- Bert Vaes (ORCID: https://orcid.org/0000-0001-5244-1930)
- Jean‐Marie Degryse (ORCID: https://orcid.org/0000-0002-6813-1053)
- Christophe de Terwangne (ORCID: https://orcid.org/0000-0001-9872-1989)
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- Department of Public Health (MM)
- UCLouvain (BE)
- KU Leuven (BE)
Publication Details
- Journal
- BMC Geriatrics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1186/s12877-025-06699-7
- Citations
- 1
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 1.22
Funders
- Koning Boudewijnstichting