Association of regular paracetamol or ibuprofen usage with the risk of incident kidney stones
Regular paracetamol usage, but not ibuprofen usage, was associated with an increased risk of incident kidney stones. These findings suggest that caution is warranted regarding regular paracetamol usage, particularly in individuals at risk for kidney stones.
Authors
- Xiaoqin Gan (ORCID: https://orcid.org/0009-0002-1906-666X)
- Xianhui Qin (ORCID: https://orcid.org/0000-0001-7812-7982)
- Chun Zhou (ORCID: https://orcid.org/0009-0009-0575-4841)
- Yu Huang (ORCID: https://orcid.org/0000-0002-3875-7581)
- Yiting Wu (ORCID: https://orcid.org/0000-0001-8079-9497)
- Ziliang Ye (ORCID: https://orcid.org/0000-0001-8314-6977)
- Sisi Yang (ORCID: https://orcid.org/0009-0008-2696-9107)
- Yuanyuan Zhang (ORCID: https://orcid.org/0000-0002-9894-248X)
- Yiwei Zhang (ORCID: https://orcid.org/0000-0001-9611-9337)
- Hao Xiang (ORCID: https://orcid.org/0000-0003-4823-2890)
Institutions
- National Clinical Research Center for Digestive Diseases (CN)
- Nanfang Hospital (CN)
- Guangdong Provincial Center for Disease Control and Prevention (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- British Journal of Clinical Pharmacology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/bcp.70342
- Primary Topic
- Kidney Stones and Urolithiasis Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Development and Reform Commission of Shenzhen Municipality
- Project 211