American Society of Hematology 2025 guidelines for treating newly diagnosed acute myeloid leukemia in older adults
Key recommendations of these guidelines include treatment over best supportive care; venetoclax-based regimens over monotherapies; and incorporation of FLT3 inhibitors into traditional induction and postremission therapy.
Authors
- Jacqueline Suen Garcia (ORCID: https://orcid.org/0000-0003-2118-6302)
- Romina Brignardello‐Petersen (ORCID: https://orcid.org/0000-0002-6010-9900)
- Ryan J. Mattison (ORCID: https://orcid.org/0000-0001-8574-8365)
- Mohamed L. Sorror (ORCID: https://orcid.org/0000-0001-5260-1981)
- Charles Foucar (ORCID: https://orcid.org/0000-0001-7972-6979)
- Andrés Gómez‐De León (ORCID: https://orcid.org/0000-0001-6904-9345)
- Luke B. Fletcher (ORCID: https://orcid.org/0000-0002-2384-536X)
- Sara Ibrahim (ORCID: https://orcid.org/0000-0002-7713-6171)
- Chong Chyn Chua (ORCID: https://orcid.org/0000-0002-2162-3288)
- Jeffrey E. Lancet (ORCID: https://orcid.org/0000-0002-7751-7310)
- Kah Poh Loh (ORCID: https://orcid.org/0000-0002-6978-0418)
- Yetiani Roldán (ORCID: https://orcid.org/0009-0009-4564-5973)
- Maria R. Baer (ORCID: https://orcid.org/0000-0002-9499-1348)
- Mikkael Aaron Sekeres (ORCID: https://orcid.org/0000-0003-2009-6524)
- Andrew Artz (ORCID: https://orcid.org/0000-0003-0803-9607)
- María José Oliveros (ORCID: https://orcid.org/0000-0002-9327-6844)
- Luca Malcovati (ORCID: https://orcid.org/0000-0002-1460-1611)
- Sara Tinsley (ORCID: https://orcid.org/0000-0003-3012-7398)
- Bernard L. Marini (ORCID: https://orcid.org/0000-0003-0436-8948)
- Uwe Platzbecker (ORCID: https://orcid.org/0000-0003-1863-3239)
- Roberta Demichelis‐Gómez (ORCID: https://orcid.org/0000-0003-0258-7397)
- Pamela Egan (ORCID: https://orcid.org/0000-0001-8590-2916)
- Gordon H. Guyatt
- John Treitz
- Linda Gilberto
Institutions
- Universidad de La Frontera (CL)
- University of Maryland, Baltimore (US)
- City Of Hope National Medical Center (US)
- University of Wisconsin–Madison (US)
- University of Louisville (US)
- University of Miami (US)
- Universidad Autónoma de Nuevo León (MX)
- University of New Mexico (US)
- University of Washington (US)
- University of Pavia (IT)
- University of Michigan (US)
- University of Florida Health (US)
- University of Rochester Medical Center (US)
- Moffitt Cancer Center (US)
- Fred Hutch Cancer Center (US)
- University Hospital Foundation (CA)
- United States House of Representatives (US)
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Monash Children’s Hospital (AU)
- MaineHealth (US)
- City of Hope (US)
- Michigan United (US)
- Michigan Medicine (US)
- Dana-Farber Cancer Institute (US)
- Monash Health (AU)
- Willamette Valley Cancer Institute and Research Center (US)
- Sylvester Comprehensive Cancer Center (US)
- University Hospital Carl Gustav Carus (DE)
- Sidney Kimmel Comprehensive Cancer Center (US)
- Monash University (AU)
- McMaster University (CA)
Publication Details
- Journal
- Blood Advances
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1182/bloodadvances.2025017934
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77