Systemic inflammatory and oxidative stress alterations in recent-onset psychosis: findings from a non-smoking case-control sample
MMP-9 levels are elevated in recent-onset psychosis, independent of smoking. Our findings underscore the importance of accounting for clinical and metabolic heterogeneity when interpreting peripheral biomarkers in psychosis.
Authors
- Anja Lok (ORCID: https://orcid.org/0000-0002-0560-9603)
- Harry van Goor (ORCID: https://orcid.org/0000-0002-6670-1577)
- Nico J. van Beveren
- Arno R. Bourgonje (ORCID: https://orcid.org/0000-0001-5754-3821)
- René Lutter (ORCID: https://orcid.org/0000-0002-6243-9911)
- Lieuwe de Haan (ORCID: https://orcid.org/0000-0002-3820-7926)
- Hanno L. Tan (ORCID: https://orcid.org/0000-0002-7905-5818)
- Arjen L. Sutterland (ORCID: https://orcid.org/0000-0001-9206-2492)
- Julia M. Hagen
- Daphne A M Dielemans
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Parnassia Groep (NL)
- Arkin (NL)
- Reinier van Arkel (NL)
- Amsterdam University Medical Centers (NL)
- Parnassia Groep Academie
- University of Amsterdam (NL)
Publication Details
- Journal
- Psychiatry Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.psychres.2025.116866
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00