Integrating spot-scanning proton arc therapy with functional avoidance strategies to reduce pulmonary toxicity
Our study highlighted the potential of SPArc to spare dose to functional lung. NTCP results further indicated that the risk of pulmonary complications can be reduced with SPArc compared to photon or IMPT for functional avoidance radiotherapy.
Authors
- Peilin Liu (ORCID: https://orcid.org/0000-0001-8338-0886)
- Yevgeniy Vinogradskiy
- Edward Castillo (ORCID: https://orcid.org/0000-0003-0523-487X)
- Craig Stevens
- Xuanfeng Ding (ORCID: https://orcid.org/0000-0002-1733-6278)
- Richard Castillo (ORCID: https://orcid.org/0000-0001-6541-6021)
- Xiaojun Xu (ORCID: https://orcid.org/0000-0002-0127-2812)
- Xiaoqiang Li (ORCID: https://orcid.org/0000-0002-9692-1458)
- Xiaoda Cong (ORCID: https://orcid.org/0009-0003-5175-630X)
- Yingxuan Chen (ORCID: https://orcid.org/0000-0003-1617-9001)
- Inga S. Grills
Institutions
- Thomas Jefferson University (US)
- Emory University (US)
- Beaumont Hospital, Royal Oak (US)
- The University of Texas at Austin (US)
Publication Details
- Journal
- Physics and Imaging in Radiation Oncology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.phro.2025.100876
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00