Plants with promising antileishmanial activity in Colombia: A systematic review and meta-analysis

Colombian plants represent a promising source of leishmanicidal agents, with several species exhibiting strong <i>in vitro</i> antileishmanial activity and remarkably high SI values. However, since SI thresholds were originally established for purified compounds, their interpretation for other plant-derived preparations should be approached with caution. Moving toward standardized assays and reporting practices will be key to translating these findings into reproducible and actionable knowledge.