Identification of hub genes contributing to acute eczema using transcriptome sequencing and machine-learning approaches
Icam1 is a key gene potentially driving inflammatory infiltration in AE and may serve as a diagnostic target. This integrative bioinformatics-experimental approach provides a robust framework for discovering pathogenic genes in inflammatory skin diseases.
Authors
- Xiaona Ye
- Yingying Zhao
- Xinying Li (ORCID: https://orcid.org/0000-0001-9835-2191)
- Wenxiu Wang (ORCID: https://orcid.org/0000-0002-9268-3528)
- Xingjun Han
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1186/s12920-025-02283-5
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00