Neuroform Atlas single-stent coiling for wide-neck MCA bifurcation aneurysms: a retrospective single-centre case series

Wide-neck aneurysms at the middle cerebral artery (MCA) bifurcation pose a recognised challenge for endovascular treatment. Y- or X-stent configurations can reconstruct the bifurcation but increase procedural complexity and complication risk. The Neuroform Atlas is a low-profile, open-cell stent that allows single-stent neck reconstruction through 0.0165-inch microcatheters. Evidence on its performance in Chinese patients remains limited. We conducted a retrospective, single-centre case series of 15 consecutive patients with wide-neck MCA bifurcation aneurysms treated with Neuroform Atlas stent-assisted coiling at the Aviation General Hospital (Beijing, China) between October 2023 and February 2025. Inclusion criteria were aneurysm neck > 4 mm or dome-to-neck ratio < 1.5, age 18–75 years and ability to comply with follow-up; both ruptured (Hunt–Hess I–III) and unruptured aneurysms were included. Fourteen aneurysms were treated with a single stent and one required Y-stenting. The primary endpoint was complete occlusion (Raymond grade I) at 6-month angiographic follow-up; secondary endpoints included periprocedural thromboembolic or haemorrhagic events, functional outcome measured by the modified Rankin Scale (mRS) and the need for retreatment. Data were summarised descriptively. Patients had a median age of 61 years (range 30–75 years) and were predominantly female (73 %). Aneurysms had a median neck width of 4.2 mm and mean maximum diameter of 5.16 mm; 40 % presented with subarachnoid haemorrhage. Technical success was 100 %, with 14/15 aneurysms treated using a single stent. Immediate or follow-up angiography showed Raymond grade I occlusion in all cases. No periprocedural thromboembolic or haemorrhagic events were observed, all patients achieved mRS ≤ 2 at last follow-up, and no recurrences or retreatments were required. In this small retrospective series, Neuroform Atlas single-stent-assisted coiling was feasible and achieved complete occlusion with no procedure-related complications in wide-neck MCA bifurcation aneurysms. These preliminary results suggest the approach may offer a safe and effective alternative to complex dual-stenting techniques, but larger prospective studies with control groups are needed to confirm its generalisability. • Evaluation of Neuroform Atlas Stent: This study investigates the safety and efficacy of the Neuroform Atlas stent-assisted coiling technique for treating wide-necked aneurysms at the bifurcation of the middle cerebral artery. • Successful Immediate and Long-Term Results: The technique demonstrated both immediate and long-term success, with no major complications observed during surgery or postoperative follow-up. • Minimal Invasiveness and Shorter Recovery: Neuroform Atlas stent-assisted coiling offers a safer, more effective alternative to traditional surgical clipping, with advantages such as minimal invasiveness and shorter recovery time. • No Thrombotic or Hemorrhagic Complications: The study observed no thrombotic or hemorrhagic complications, emphasizing the importance of strict perioperative management, including antiplatelet therapy and intraoperative heparinization. • Long-Term Follow-Up: Long-term follow-up confirmed no aneurysm recurrence or in-stent re-stenosis, supporting the technique's safety and efficacy in managing complex aneurysms.

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Journal
Medicine in Novel Technology and Devices
Published
2025-12-01
DOI
https://doi.org/10.1016/j.medntd.2025.100417
Primary Topic
Intracranial Aneurysms: Treatment and Complications
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article
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article

Neuroform Atlas single-stent coiling for wide-neck MCA bifurcation aneurysms: a retrospective single-centre case series

Lei Liu, Hao Sun, Huang Zhiyong, Jiaxi Liu et al.
Medicine in Novel Technology and Devices
Intracranial Aneurysms: Treatment and Complications
article

Neuroform Atlas single-stent coiling for wide-neck MCA bifurcation aneurysms: a retrospective single-centre case series

Lei Liu, Hao Sun, Huang Zhiyong, Jiaxi Liu, Bing Huang, An Jianlei, Guo Dejiang, Chen Shuchao
article en

Abstract

Wide-neck aneurysms at the middle cerebral artery (MCA) bifurcation pose a recognised challenge for endovascular treatment. Y- or X-stent configurations can reconstruct the bifurcation but increase procedural complexity and complication risk. The Neuroform Atlas is a low-profile, open-cell stent that allows single-stent neck reconstruction through 0.0165-inch microcatheters. Evidence on its performance in Chinese patients remains limited. We conducted a retrospective, single-centre case series of 15 consecutive patients with wide-neck MCA bifurcation aneurysms treated with Neuroform Atlas stent-assisted coiling at the Aviation General Hospital (Beijing, China) between October 2023 and February 2025. Inclusion criteria were aneurysm neck > 4 mm or dome-to-neck ratio < 1.5, age 18–75 years and ability to comply with follow-up; both ruptured (Hunt–Hess I–III) and unruptured aneurysms were included. Fourteen aneurysms were treated with a single stent and one required Y-stenting. The primary endpoint was complete occlusion (Raymond grade I) at 6-month angiographic follow-up; secondary endpoints included periprocedural thromboembolic or haemorrhagic events, functional outcome measured by the modified Rankin Scale (mRS) and the need for retreatment. Data were summarised descriptively. Patients had a median age of 61 years (range 30–75 years) and were predominantly female (73 %). Aneurysms had a median neck width of 4.2 mm and mean maximum diameter of 5.16 mm; 40 % presented with subarachnoid haemorrhage. Technical success was 100 %, with 14/15 aneurysms treated using a single stent. Immediate or follow-up angiography showed Raymond grade I occlusion in all cases. No periprocedural thromboembolic or haemorrhagic events were observed, all patients achieved mRS ≤ 2 at last follow-up, and no recurrences or retreatments were required. In this small retrospective series, Neuroform Atlas single-stent-assisted coiling was feasible and achieved complete occlusion with no procedure-related complications in wide-neck MCA bifurcation aneurysms. These preliminary results suggest the approach may offer a safe and effective alternative to complex dual-stenting techniques, but larger prospective studies with control groups are needed to confirm its generalisability. • Evaluation of Neuroform Atlas Stent: This study investigates the safety and efficacy of the Neuroform Atlas stent-assisted coiling technique for treating wide-necked aneurysms at the bifurcation of the middle cerebral artery. • Successful Immediate and Long-Term Results: The technique demonstrated both immediate and long-term success, with no major complications observed during surgery or postoperative follow-up. • Minimal Invasiveness and Shorter Recovery: Neuroform Atlas stent-assisted coiling offers a safer, more effective alternative to traditional surgical clipping, with advantages such as minimal invasiveness and shorter recovery time. • No Thrombotic or Hemorrhagic Complications: The study observed no thrombotic or hemorrhagic complications, emphasizing the importance of strict perioperative management, including antiplatelet therapy and intraoperative heparinization. • Long-Term Follow-Up: Long-term follow-up confirmed no aneurysm recurrence or in-stent re-stenosis, supporting the technique's safety and efficacy in managing complex aneurysms.

Medicine in Novel Technology and DevicesVol. 29
Hebei North University (CN), Chinese PLA General Hospital (CN), Aviation General Hospital (CN)
Openalex Percentile: Top 49%
Intracranial Aneurysms: Treatment and Complications
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