Intensity-Modulated Proton Therapy for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
IMPT offers excellent local control and a favorable safety profile in patients with HCC and PVTT, with the potential to downstage tumors for curative interventions. These findings, though limited by the retrospective design and heterogeneity of systemic therapies, support the integration of IMPT into multidisciplinary treatment strategies and highlight the need for prospective studies to clarify its role alongside systemic therapy.
Authors
- Chieh-Min Liu (ORCID: https://orcid.org/0000-0001-6367-5804)
- Sheng‐Nan Lu (ORCID: https://orcid.org/0000-0002-5493-4752)
- Chao‐Hung Hung (ORCID: https://orcid.org/0000-0003-1646-9519)
- Hsin‐You Ou (ORCID: https://orcid.org/0000-0002-6992-6253)
- Yen‐Hao Chen (ORCID: https://orcid.org/0000-0002-5622-5490)
- Bing‐Shen Huang (ORCID: https://orcid.org/0000-0002-0477-448X)
- Chen Wy (ORCID: https://orcid.org/0000-0002-2483-8292)
- Jen-Yu Cheng (ORCID: https://orcid.org/0000-0002-5080-0394)
- Chia‐Hsuan Lai
- Yu‐Ming Wang (ORCID: https://orcid.org/0000-0002-2441-7551)
- Tsung‐Hui Hu
- Eng-Yen Huang
Institutions
- National Sun Yat-sen University (TW)
- National Taiwan University (TW)
- Chang Gung University (TW)
- Kaohsiung Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- National Taiwan University Hospital (TW)
- Chiayi Chang Gung Memorial Hospital (TW)
- Fooyin University (TW)
- Cheng Shiu University (TW)
Publication Details
- Journal
- Journal of Hepatocellular Carcinoma
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/jhc.s551113
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chang Gung Medical Foundation