Integrated Bioinformatics Identifies NLRP3 Inflammasome Hub Genes and Therapeutic Targets in Schizophrenia
Five genes (HSPA8, SCAP, FLNA, TRAF2, PINK1-AS) were identified as potential novel biomarkers and therapeutic targets for SZ, providing a theoretical foundation for elucidating disease mechanisms and advancing precision medicine in SZ.
Authors
- Mengdi Liu (ORCID: https://orcid.org/0009-0000-4646-6533)
- Yongchun Cui (ORCID: https://orcid.org/0000-0002-2375-5778)
- Xinying Li (ORCID: https://orcid.org/0000-0003-4967-4404)
- Jiawei Ma (ORCID: https://orcid.org/0000-0002-0596-770X)
- Jinhui Wang (ORCID: https://orcid.org/0000-0003-1512-827X)
- Yan Ren (ORCID: https://orcid.org/0000-0002-1937-5019)
- Ruiyuan Liu (ORCID: https://orcid.org/0000-0003-4807-4909)
- Lin Kong
Institutions
- Shanxi Medical University (CN)
- Shanxi Academy of Medical Sciences (CN)
- Fourth People's Hospital of Taiyuan (CN)
Publication Details
- Journal
- Neuropsychiatric Disease and Treatment
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ndt.s555802
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00