The impact of androgen deprivation therapy and novel hormonal therapy on thyroid hormone levels in prostate cancer patients: a systematic review and meta-analysis

For the first time, we showed no significant difference in the TSH level between the two groups, which might indicate that the TSH level was not affected by ADT in PC patients. Notably, in European countries, patients with long-term ADT were more likely to have lower FT4 levels than non-ADT patients were, but interestingly, all FT4 levels were within their reference intervals.