Biological Features of KLC2 Mutations in Chronic Myeloid Leukemia and Their Contribution to Inducing Drug Resistance
This study demonstrates the biological and functional importance of KLC2 mutation in CML cells, potentially enabling the development of better treatment strategies for CML patients carrying <i>KLC2</i> mutations and providing enhanced understanding of the disease progression.
Authors
- Rabindranath Bera (ORCID: https://orcid.org/0000-0002-4185-8690)
- Yotaro Ochi (ORCID: https://orcid.org/0000-0001-8472-6164)
- Kenichi Yoshida (ORCID: https://orcid.org/0000-0003-4612-2778)
- Seishi Ogawa (ORCID: https://orcid.org/0000-0002-7778-5374)
- Ying‐Jung Huang
- Lee‐Yung Shih (ORCID: https://orcid.org/0000-0003-1866-7922)
- Ming‐Chung Kuo
Institutions
- Chang Gung University (TW)
- Kyoto University (JP)
- Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- National Cancer Research Institute (GB)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.32604/or.2025.070259
- Primary Topic
- Chronic Myeloid Leukemia Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00