Abstract 54: Exploring the Use and Reporting of Cancer Registry Data by the Caribbean Region in Peer-Reviewed Literature: A Scoping Review

Abstract Purpose: To conduct a scoping review of peer-reviewed publications that have used data from Caribbean cancer registries (CR). The overall goal is to capture the reach of Caribbean CR data, characterize the type of information disseminated, and identify knowledge gaps. Methods: We searched PubMed, Scopus, Web of Science: Core Collection and LILACS, and included full-text articles in English, French, or Spanish, published between 2003–2023, that used data from a CR based in at least one Caribbean country or territory. The screening process was completed in two stages using Covidence (screening at abstract and full text levels) by two reviewers independently. Data was extracted from each full text of included articles using a standardized, predefined form in Covidence by two reviewers. Results: A total of 127 articles met the inclusion criteria. CR data from 1958 to 2018 were reported. Of the 33 Caribbean countries and territories included, 14 had published at least one article. Almost all publications (96%) used data from population-based CR (PBCR). Three of the countries/territories with PBCRs had <3 publications and three had no publications. Breast, cervical, and colorectal cancers were the most reported. The most reported factors of interest assessed were tumor characteristics, followed by environment and socioeconomic status. Conclusion: This scoping review shows that while Caribbean cancer registries have contributed substantially to the peer-reviewed literature, this is limited to less than half of the region. Several countries/territories with PBCRs had low or no publications represented. The research published presents important research on cancer types of interest for the region, and possible associations with important risk factors. Continued efforts are needed to strengthen, support, and sustain high-quality PBCRs in the Caribbean, as well as the use and dissemination of this data to fill knowledge gaps and prioritize key research questions and cancer control policies. Citation Format: Rachel A. Hanisch, Sarah Quesnel-Crooks, Linsey Eldridge, Ann Chao, Madison N. Behm, Brenda K. Edwards, Sara Benitez Majano, Alicia A. Livinski. Exploring the Use and Reporting of Cancer Registry Data by the Caribbean Region in Peer-Reviewed Literature: A Scoping Review [abstract]. In: Proceedings of the 13th Annual Symposium on Global Cancer Research; 2025 Sep 16. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2025;34(12_Suppl):Abstract nr 54.