Striatal M4 muscarinic receptors determine the biological rhythm of activity, with a supportive role of M1 muscarinic receptors
We conclude that muscarinic receptor-directed biological rhythm of activity is determined in the striatum (caudate ncl-putamen) as a key structure mainly by M<sub>4</sub> mAChRs with a supportive role of M<sub>1</sub> mAChRs.
Authors
- J Mysliveček (ORCID: https://orcid.org/0000-0002-4275-4607)
- Katerina Janisova
- Sándor T. Forczek (ORCID: https://orcid.org/0000-0001-5023-9691)
- Monika Uhlířová (ORCID: https://orcid.org/0000-0002-1084-9070)
Institutions
- Charles University (CZ)
- Czech Academy of Sciences, Institute of Experimental Botany (CZ)
- Czech Academy of Sciences, Institute of Physiology (CZ)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.3389/fphar.2025.1691118
- Citations
- 1
- Primary Topic
- Receptor Mechanisms and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Univerzita Karlova v Praze