Construction and validation of a cognitive frailty risk prediction model for elderly patients with colorectal cancer
The risk of CF in elderly patients with colorectal cancer is relatively high, and it is related to factors such as age, chemotherapy history, tumor stage, whether engaging in intellectual activities, social support level, and educational level. The risk prediction model for CF in elderly patients with CRC developed in this study exhibits good predictive performance in both internal and external validations. The prediction model constructed in this study can provide a reference for healthcare providers to early identify high-risk individuals and implement targeted intervention measures.
Authors
- Dawei Xie (ORCID: https://orcid.org/0000-0002-5065-7305)
- O.H. Chen
- Shi Yao (ORCID: https://orcid.org/0000-0002-4574-8106)
- Yunhong Du
- Weiqi Rong (ORCID: https://orcid.org/0000-0002-1127-1709)
- Jianwei Li (ORCID: https://orcid.org/0000-0003-2999-6932)
- Wei Liu (ORCID: https://orcid.org/0000-0002-4841-8356)
- Yu Wang (ORCID: https://orcid.org/0000-0001-7894-6523)
- Xiujie Zhang (ORCID: https://orcid.org/0000-0002-0873-7977)
- Lili Sun (ORCID: https://orcid.org/0000-0002-0160-4880)
- Lili Peng
- Xiaoye Ma
- Li Wang (ORCID: https://orcid.org/0000-0003-2068-7535)
Institutions
- Qingdao University (CN)
- Shandong University of Traditional Chinese Medicine (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- Second Military Medical University (CN)
- Dalian Medical University (CN)
- Changhai Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-12-01
- DOI
- https://doi.org/10.3389/fnagi.2025.1692414
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00