Decoding the therapeutic potential mechanism of Cornus officinalis in Parkinson’s disease: a network pharmacology insight
<i>Cornus officinalis</i> exhibits potential therapeutic effects against PD through multi-target and multi-pathway mechanisms, including anti-inflammatory actions, regulation of synaptic function regulation, and metabolic modulation. These findings provide a theoretical foundation for further experimental and clinical validation of <i>Cornus officinalis</i> as a promising candidate for PD treatment.
Authors
- Yalan Deng (ORCID: https://orcid.org/0000-0002-3954-3243)
- Zheng Huan Wu
- Yingmei Feng (ORCID: https://orcid.org/0000-0001-5248-0155)
- Jiwei Zhao (ORCID: https://orcid.org/0000-0002-9298-9412)
- Taotao Zhou (ORCID: https://orcid.org/0000-0002-2881-4781)
- Wen Wang (ORCID: https://orcid.org/0000-0003-4120-0773)
- Yuan Dong (ORCID: https://orcid.org/0000-0001-6579-6466)
- Yao Feng (ORCID: https://orcid.org/0000-0002-0888-8775)
Institutions
- Capital Medical University (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.3389/fphar.2025.1714796
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00