The roles of both the endogenous synthesis and exogenous uptake of fatty acids in thyroid cancer cell proliferation
Both the de novo synthesis and exogenous uptake of FAs are important for PTC cell proliferation. The combined inhibition of LPL and FASN inhibitors shows promise for PTC treatment.
Authors
- Xianjiao Cao (ORCID: https://orcid.org/0000-0003-3479-9212)
- Sijuan Chen
- Wei Bi (ORCID: https://orcid.org/0000-0003-3472-8801)
- Chenyu Li (ORCID: https://orcid.org/0000-0001-8028-6691)
- Xiaolei Li (ORCID: https://orcid.org/0000-0002-2697-6496)
- Yiming Chen (ORCID: https://orcid.org/0000-0003-2148-6049)
- Guandong Xu
Institutions
- Qingdao University (CN)
- 117th Hospital of People's Liberation Army (CN)
- People's Liberation Army No. 150 Hospital (CN)
- People's Liberation Army 401 Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1186/s40001-025-03582-4
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00