<scp>DL</scp> ‐3‐n‐Butylphthalide Protects Mitochondria Against Ischemia/Hypoxia Damage via Suppressing <scp>GCN5L1</scp> ‐Mediated Drp1 Acetylation in Neurons and Mouse Brains
Our findings provide a novel insight into the molecular mechanism whereby NBP protects mitochondria against ischemia/hypoxia damage, offering a promising drug for mitochondria-targeting therapeutics for ischemic stroke.
Authors
- Ya Wen (ORCID: https://orcid.org/0009-0001-2339-5549)
- Ning Zhang (ORCID: https://orcid.org/0000-0002-9513-9288)
- Lei Wang (ORCID: https://orcid.org/0000-0002-5071-5800)
- Haitao Zhang (ORCID: https://orcid.org/0000-0002-5228-8451)
- Shan Wang
- Jiejie Zhang (ORCID: https://orcid.org/0009-0006-1419-0636)
- Xiaotong Yang (ORCID: https://orcid.org/0009-0001-2323-2619)
- Xiaoli Ge (ORCID: https://orcid.org/0009-0004-0533-3696)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- Hebei Meteorological Bureau (CN)
- Hebei Seismological Bureau (CN)
- Hebei Science and Technology Department (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-11-30
- DOI
- https://doi.org/10.1002/cns.70682
- Citations
- 1
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.84