U-shaped association between BMI and cognitive impairment in middle-aged and older adults with type 2 diabetes: effect modification by lifestyle and exercise

Observations indicate that the U-shaped relationship between cognitive impairment and BMI observed in middle-aged and older adults with type 2 diabetes was more pronounced in those who live alone and are physically inactive. Although the interaction test was not significant, the subgroup analysis suggested that middle-aged and older adults with type 2 diabetes who live alone and are physically inactive may need to manage their BMI more rigorously.