In silico design of novel precision vaccine targeting sclerostin epitopes for osteoporosis prevention and treatment
The SOST-targeted vaccination strategy offers a promising and cost-effective approach for the early prevention and sustained management of osteoporosis, demonstrating substantial potential for clinical translation.
Authors
- Jianzhou Luo (ORCID: https://orcid.org/0009-0000-1302-4448)
- Bin Guan (ORCID: https://orcid.org/0000-0002-5210-6216)
- Lin Li (ORCID: https://orcid.org/0000-0002-2516-5827)
- Huiren Tao
- Tailin Wu
- Zili Yang
Institutions
- University of Hong Kong - Shenzhen Hospital (CN)
- Shenzhen University Health Science Center (CN)
- Community Health Center (US)
- Xi'an Jiaotong University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.3389/fimmu.2025.1644437
- Citations
- 1
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.81