A prospective single-arm study on the effects of repeated intravenous infusions of canine adipose-derived mesenchymal stromal cells in dogs with chronic inflammatory enteropathy
Repeated intravenous infusions of allogeneic adipose-derived MSCs led to a clinical improvement in some dogs with refractory CIE without marked acute adverse events. Our results suggest that MSC therapy is particularly effective for CIE dogs with hypoalbuminemia.
Authors
- Masaki Michishita (ORCID: https://orcid.org/0000-0002-0353-3668)
- Hirotaka Matsumoto (ORCID: https://orcid.org/0000-0002-8832-6341)
- Yuyo Yasumura (ORCID: https://orcid.org/0000-0002-3028-779X)
- Takahiro Teshima (ORCID: https://orcid.org/0000-0001-9646-6785)
- Ryohei H. Suzuki (ORCID: https://orcid.org/0000-0001-9451-5854)
Institutions
- Nippon Veterinary and Life Science University (JP)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1186/s13287-025-04842-0
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00