A Case of Macular Hole in a Vitrectomized Eye: Case Report

Purpose: To report a case of pharmacological treatment of a macular hole in a vitrectomized eye.Case summary: A 42-year-old woman who had undergone vitrectomy for rhegmatogenous retinal detachment in her right eye one year prior presented with decreased visual acuity in that eye.Fundus examination revealed an epiretinal membrane, subretinal fluid, and cystoid macular edema (CME) in the right eye.Blood tests and fluorescein angiography showed no other abnormalities.After initiating oral prednisolone 40 mg, the CME improved, and the steroid dose was gradually tapered.However, two months later, a full-thickness macular hole and recurrent CME were observed, leading to re-administration of oral prednisolone (40 mg).One month later, CME worsened, and there was no improvement in the macular hole; thus, surgical intervention was planned.However, one week later, preoperative examination showed resolution of both the full-thickness macular hole and CME, and surgery was canceled.Oral prednisolone was gradually tapered.Over a one-year follow-up period, the macular hole remained closed without recurrence.Conclusions: We report a case of macular hole closure following pharmacological management in a vitrectomized eye.In cases of macular hole with concurrent CME in vitrectomized eyes, pharmacological management of the edema and observation for potential hole closure may be considered prior to surgical intervention.