Psychotic or Not, Mania Hurts: A 5‐Year Cohort Study With a Spotlight on the Non‐Psychotic Subtype and Mixed Features
While psychotic and non-psychotic mania show clinical and therapeutical differences, psychosis may not predict short- to medium-term outcomes. Non-psychotic mania-which is associated with depressive polarity, mixed features and suicidal behaviour-may indicate a clinically relevant and therapeutically challenging but underrecognized subgroup. These findings call for a nuanced comprehension of the impact of psychosis in mania and multidimensional approaches.
Authors
- Tabatha Fernández‐Plaza (ORCID: https://orcid.org/0000-0003-4572-8946)
- Lluc Colomer (ORCID: https://orcid.org/0000-0001-9964-0822)
- Anna Giménez‐Palomo (ORCID: https://orcid.org/0000-0002-9474-6473)
- Òscar de Juan
- S. Salmerón (ORCID: https://orcid.org/0000-0002-0212-4491)
- Eduard Vieta (ORCID: https://orcid.org/0000-0002-0548-0053)
- H. Andreu Gracia (ORCID: https://orcid.org/0009-0004-3420-6231)
- Isabella Pacchiarotti (ORCID: https://orcid.org/0000-0002-7822-0367)
- Iñaki Ochandiano (ORCID: https://orcid.org/0009-0004-1550-8664)
- Luis Olivier (ORCID: https://orcid.org/0000-0002-5304-1338)
Institutions
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Hospital Clínic de Barcelona (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Acta Psychiatrica Scandinavica
- Published
- 2025-11-30
- DOI
- https://doi.org/10.1111/acps.70049
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministerio de Ciencia, Innovación y Universidades
- Centres de Recerca de Catalunya
- European Commission
- Generalitat de Catalunya
- Ministerio de Ciencia e Innovación
- Centro de Investigación Biomédica en Red de Salud Mental
- Instituto de Salud Carlos III
- European Regional Development Fund
- European Social Fund