Wogonin pretreatment of infrapatellar fat pad mesenchymal stem cell-derived exosomes advances articular cartilage repair in osteoarthritis
Wogonin pretreatment significantly enhances the ability of MSC<sup>IPFP</sup>-Exo to promote cartilage defect repair, and it is expected to be a promising agent for the clinical treatment of OA. Further preclinical and clinical studies are necessary to validate the safety, efficacy, and long-term outcomes of this therapeutic approach before its translation into clinical practice for the treatment of OA.
Authors
- Wenzhao Li
- Tao Cheng (ORCID: https://orcid.org/0000-0003-4855-0020)
- Minzhi Mao (ORCID: https://orcid.org/0000-0002-0392-1652)
- Kewei Zhu
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Bone and Joint Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1302/2046-3758.1412.bjr-2024-0316.r2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00