When the Eyes Deceive: Uncommon Ophthalmic Presentation of Giant Cell Arteritis

Giant cell arteritis (GCA) is a systemic granulomatous large vessel vasculitis that predominantly affects older adults. We present a rare case of a patient in her 60s who presented with hypertension and isolated cranial nerve (CN) IV palsy. Initial imaging and temporal artery biopsy performed were negative. Her symptoms then resurfaced again after her prednisolone was stopped. Re-commencement of steroids led to a quick resolution of her visual symptoms and headaches within a matter of days. This case highlights the importance of clinical judgement and prompt initiation of steroids without delay. A gradual and prolonged steroid tapering regime is also essential to avoid visual loss, the most feared complication in GCA.

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Publication Details

Journal
Cureus
Published
2025-11-30
DOI
https://doi.org/10.7759/cureus.98164
Primary Topic
Vasculitis and related conditions
Type
article
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0.00
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article

When the Eyes Deceive: Uncommon Ophthalmic Presentation of Giant Cell Arteritis

K. M. Subhani, Alison Penwarden, Timothy Anthony Yap, Leena Yalakki-Jagadeesh
Cureus
Vasculitis and related conditions
article

When the Eyes Deceive: Uncommon Ophthalmic Presentation of Giant Cell Arteritis

K. M. Subhani, Alison Penwarden, Timothy Anthony Yap, Leena Yalakki-Jagadeesh
article en

Abstract

Giant cell arteritis (GCA) is a systemic granulomatous large vessel vasculitis that predominantly affects older adults. We present a rare case of a patient in her 60s who presented with hypertension and isolated cranial nerve (CN) IV palsy. Initial imaging and temporal artery biopsy performed were negative. Her symptoms then resurfaced again after her prednisolone was stopped. Re-commencement of steroids led to a quick resolution of her visual symptoms and headaches within a matter of days. This case highlights the importance of clinical judgement and prompt initiation of steroids without delay. A gradual and prolonged steroid tapering regime is also essential to avoid visual loss, the most feared complication in GCA.

CureusVol. 17(11)
Basingstoke and North Hampshire Hospital (GB)
Openalex Percentile: Top 44%
Vasculitis and related conditions
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When the Eyes Deceive: Uncommon Ophthalmic Presentation of Giant Cell Arteritis — K. M. Subhani, Alison Penwarden, et al. · Cureus (2025) | TGRS Research Map | TGRS