Comprehensive multi-omics analysis revealed the mechanism of Panax ginseng extract in alleviating Qi deficiency liver cancer

The alleviating effect of PG on QDLC may be attributed to the activation of the HIF-1α/PPARα-mediated FAO signaling axis, which improves mitochondrial dysfunction in the liver.

Authors

Shuhua Pei
Zong Hou
Rongjin Wang (ORCID: https://orcid.org/0000-0001-8829-5322)
Shu Liu (ORCID: https://orcid.org/0000-0002-8848-6871)
Zhongying Liu
Meiyuan Wang

Institutions

Jilin University (CN)
Changchun Institute of Applied Chemistry (CN)

Publication Details

Journal: Journal of Ethnopharmacology
Published: 2025-11-30
DOI: https://doi.org/10.1016/j.jep.2025.120985
Primary Topic: Ginseng Biological Effects and Applications
Type: article
Field-Weighted Citation Impact: 0.00

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article

Comprehensive multi-omics analysis revealed the mechanism of Panax ginseng extract in alleviating Qi deficiency liver cancer

Shuhua Pei, Zong Hou, Rongjin Wang, Shu Liu et al.

Nov 30, 2025

Journal of Ethnopharmacology

Ginseng Biological Effects and Applications

article

Comprehensive multi-omics analysis revealed the mechanism of Panax ginseng extract in alleviating Qi deficiency liver cancer

Shuhua Pei, Zong Hou, Rongjin Wang, Shu Liu, Zhongying Liu, Meiyuan Wang

November 30, 2025article en

Abstract

The alleviating effect of PG on QDLC may be attributed to the activation of the HIF-1α/PPARα-mediated FAO signaling axis, which improves mitochondrial dysfunction in the liver.

Journal of EthnopharmacologyVol. 358

Jilin University (CN), Changchun Institute of Applied Chemistry (CN)

Openalex Percentile: Top 66%

Ginseng Biological Effects and Applications

DOI Open Access PDF OpenAlex

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Comprehensive multi-omics analysis revealed the mechanism of Panax ginseng extract in alleviating Qi deficiency liver cancer — Shuhua Pei, Zong Hou, et al. · Journal of Ethnopharmacology (2025) | TGRS Research Map | TGRS