Significance and stability of cerebrospinal fluid oligoclonal band patterns in multiple sclerosis

IgG OCBs were highly prevalent in MS and CIS; a single band pattern was more prevalent in CIS and other diseases than in MS. Changes in IgG OCB result were uncommon, particularly in MS. The presence of IgG OCBs is associated with lower age of onset but not with severity of MS.

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Publication Details

Journal
Multiple Sclerosis and Related Disorders
Published
2025-11-30
DOI
https://doi.org/10.1016/j.msard.2025.106893
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
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article

Significance and stability of cerebrospinal fluid oligoclonal band patterns in multiple sclerosis

Finn Thorup Sellebjerg, Melinda Magyari, Helene Højsgaard Chow, Per Soelberg Sørensen et al.
Multiple Sclerosis and Related Disorders
Multiple Sclerosis Research Studies
article

Significance and stability of cerebrospinal fluid oligoclonal band patterns in multiple sclerosis

Finn Thorup Sellebjerg, Melinda Magyari, Helene Højsgaard Chow, Per Soelberg Sørensen, Helle Bach Søndergaard, P. E. H. Jensen, V Swane
article en

Abstract

IgG OCBs were highly prevalent in MS and CIS; a single band pattern was more prevalent in CIS and other diseases than in MS. Changes in IgG OCB result were uncommon, particularly in MS. The presence of IgG OCBs is associated with lower age of onset but not with severity of MS.

Multiple Sclerosis and Related DisordersVol. 106
Copenhagen University Hospital (DK), Rigshospitalet (DK), Danish Multiple Sclerosis Center (DK)
Openalex Percentile: Top 49%
Multiple Sclerosis Research Studies
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Significance and stability of cerebrospinal fluid oligoclonal band patterns in multiple sclerosis — Finn Thorup Sellebjerg, Melinda Magyari, et al. · Multiple Sclerosis and Related Disorders (2025) | TGRS Research Map | TGRS