Clinical Accuracy and Safety Concerns Following GPT-5 Public Demonstration in Cancer Care

OpenAI's GPT-5 demonstration showed a patient uploading pathology reports to guide treatment decisions, though privacy implications were not addressed. We evaluated GPT-5 against 100 gastrointestinal oncology cases with tumor-board validation and found identical 85% concordance to GPT-4o, contradicting superiority claims. We recommend mandatory accuracy disclosures and regulatory oversight for AI health demonstrations to protect patient safety and privacy.

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Publication Details

Journal
Journal of Medical Systems
Published
2025-11-29
DOI
https://doi.org/10.1007/s10916-025-02312-x
Citations
1
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.65
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article

Clinical Accuracy and Safety Concerns Following GPT-5 Public Demonstration in Cancer Care

Michael Bitzer, Carsten Eickhoff, Ivan Capobianco, Derna Stifini et al.
1 citations
Journal of Medical Systems
Artificial Intelligence in Healthcare and Education
0.65
article

Clinical Accuracy and Safety Concerns Following GPT-5 Public Demonstration in Cancer Care

Michael Bitzer, Carsten Eickhoff, Ivan Capobianco, Derna Stifini, André L. Mihaljević, Andrea Della Penna
article en
1 citations

Abstract

OpenAI's GPT-5 demonstration showed a patient uploading pathology reports to guide treatment decisions, though privacy implications were not addressed. We evaluated GPT-5 against 100 gastrointestinal oncology cases with tumor-board validation and found identical 85% concordance to GPT-4o, contradicting superiority claims. We recommend mandatory accuracy disclosures and regulatory oversight for AI health demonstrations to protect patient safety and privacy.

Journal of Medical SystemsVol. 49(1)
STZ eyetrial (DE), University of Tübingen (DE)
Openalex Percentile: Top 19%
Artificial Intelligence in Healthcare and Education
0.65
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