Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
Our findings show that SCA patients exhibit speech dysfunction across both connected speech and sustained vowel tasks, as AVQI stands out as a key indicator, whereas CPPS and jitter track ataxic speech severity. Our findings support using acoustic measures for objectively assessing speech dysfunction and thereby informing disease monitoring and guiding future targeted therapies.
Authors
- Ami Kumar
- Sheng‐Han Kuo (ORCID: https://orcid.org/0000-0002-9412-931X)
- Priti I. Parekh
- Charlotte Hennessey
- Hannah Lee (ORCID: https://orcid.org/0000-0003-1608-6593)
- Zena Fadel
Institutions
- University of Rochester (US)
- Columbia University (US)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1002/acn3.70264
- Primary Topic
- Voice and Speech Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Brain Research Foundation
- National Ataxia Foundation
- International Essential Tremor Foundation
- Parkinson's Foundation
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke