Efficacy of Consistency Versus Switching of Biologics for Prevention of Postoperative Recurrence in Crohn’s Disease: A Multicenter Real-World Retrospective Study
In CD patients with preoperative biologic exposure, both continuing and switching biologic therapy postoperatively were effective in preventing ER, with switching showing improved endoscopic outcomes after adjustment for confounders.
Authors
- Xiujun Liao (ORCID: https://orcid.org/0000-0001-8155-2170)
- Lanxiang Zhu
- Fenfen Wang (ORCID: https://orcid.org/0000-0003-1095-8127)
- Wei Han (ORCID: https://orcid.org/0009-0009-1848-6305)
- Zhaoxiu Liu (ORCID: https://orcid.org/0000-0003-0154-5232)
- Yi Li (ORCID: https://orcid.org/0000-0001-9315-7282)
- Zhaolian Bian (ORCID: https://orcid.org/0000-0002-0802-6497)
- Cuihua Lu
- Yan Chen (ORCID: https://orcid.org/0000-0003-3457-2560)
- Yanjun Chen (ORCID: https://orcid.org/0000-0001-9030-5673)
- Juan Wu (ORCID: https://orcid.org/0000-0001-6973-4641)
- Chunjie Zhang (ORCID: https://orcid.org/0000-0002-6116-862X)
- Jing Sun (ORCID: https://orcid.org/0000-0002-4081-766X)
- Meijiao Lu (ORCID: https://orcid.org/0000-0003-1188-4246)
- L. Q. Luo (ORCID: https://orcid.org/0009-0006-4847-6771)
- Wen Tang
- Naizhong Hu
Institutions
- Nanchang University (CN)
- Anhui Medical University (CN)
- Nantong University (CN)
- Soochow University (CN)
- Affiliated Hospital of Nantong University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- First Affiliated Hospital of Soochow University (CN)
- Wuxi People's Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1093/ibd/izaf299
- Citations
- 2
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 3.63