Characterization of myocardial infarction by in vivo chemical exchange saturation transfer magnetic resonance imaging using natural D-glucose

Our preclinical study on MI demonstrated that cardiac glucoCEST MRI utilizing natural D-glucose as a biodegradable contrast agent effectively differentiates between MI regions, remote myocardium (RM), and healthy myocardium. The results were comparable to those obtained using LGE imaging.

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Publication Details

Journal
Journal of Cardiovascular Magnetic Resonance
Published
2025-11-30
DOI
https://doi.org/10.1016/j.jocmr.2025.102667
Primary Topic
Lanthanide and Transition Metal Complexes
Type
article
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article

Characterization of myocardial infarction by in vivo chemical exchange saturation transfer magnetic resonance imaging using natural D-glucose

Verena Hoerr, Jens Soltwisch, Noelia A-González, Cornelius Faber et al.
Journal of Cardiovascular Magnetic Resonance
Lanthanide and Transition Metal Complexes
article

Characterization of myocardial infarction by in vivo chemical exchange saturation transfer magnetic resonance imaging using natural D-glucose

Verena Hoerr, Jens Soltwisch, Noelia A-González, Cornelius Faber, Michael Kuhlmann, Ajay Peddi, Daniel Schache, Klaus Dreisewerd, Lydia Sorokin, Stephan Niland, Sai Kiran Reddy Samawar, Uwe Kärst, Moritz Wildgruber, Ali Nahardani, Emily Hoffmann, Peter Niehaus, Michael Schaefers, Chris Lippe
article en

Abstract

Our preclinical study on MI demonstrated that cardiac glucoCEST MRI utilizing natural D-glucose as a biodegradable contrast agent effectively differentiates between MI regions, remote myocardium (RM), and healthy myocardium. The results were comparable to those obtained using LGE imaging.

Journal of Cardiovascular Magnetic ResonanceVol. 28(1)
University of Münster (DE), University Hospital Bonn (DE), Physiological Society (GB), Augenstern (DE), University Hospital Münster (DE), Institute of Medical Microbiology and Hygiene (DE), Ludwig-Maximilians-Universität München (DE)
Openalex Percentile: Top 69%
Lanthanide and Transition Metal Complexes
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