A Rare Triad of Congenital Facial, Abducens, and Hypoglossal Nerve Palsies: A Case Report

Moebius syndrome is a rare congenital neurological disorder characterized primarily by nonprogressive facial and abducens nerve palsy. Involvement of additional cranial nerves is uncommon. We describe an eight-year-old boy presenting with left-sided facial nerve palsy, hypoglossal nerve atrophy, and absence of the abducens nerve. Clinical examination revealed facial deviation, restricted ocular abduction, tongue atrophy, and feeding and speech difficulties - features consistent with a mild Moebius spectrum. MRI demonstrated hypoplasia of the left facial nerve, absence of the left abducens nerve, and atrophy of the right half of the tongue, confirming hypoglossal involvement. This case underscores the importance of early recognition and detailed MRI evaluation to detect atypical cranial nerve anomalies in children with Moebius syndrome.

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Publication Details

Journal
Cureus
Published
2025-11-29
DOI
https://doi.org/10.7759/cureus.98120
Primary Topic
Pectus Deformity Diagnosis and Treatment
Type
article
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article

A Rare Triad of Congenital Facial, Abducens, and Hypoglossal Nerve Palsies: A Case Report

Archana Malik, Mohammad Javed Ansari, Soumi Kundu, Pradosh Kumar Sarangi et al.
Cureus
Pectus Deformity Diagnosis and Treatment
article

A Rare Triad of Congenital Facial, Abducens, and Hypoglossal Nerve Palsies: A Case Report

Archana Malik, Mohammad Javed Ansari, Soumi Kundu, Pradosh Kumar Sarangi, Sarthak Das, Saroj Kumar Tripathy, Winnie Koshy Binoj
article en

Abstract

Moebius syndrome is a rare congenital neurological disorder characterized primarily by nonprogressive facial and abducens nerve palsy. Involvement of additional cranial nerves is uncommon. We describe an eight-year-old boy presenting with left-sided facial nerve palsy, hypoglossal nerve atrophy, and absence of the abducens nerve. Clinical examination revealed facial deviation, restricted ocular abduction, tongue atrophy, and feeding and speech difficulties - features consistent with a mild Moebius spectrum. MRI demonstrated hypoplasia of the left facial nerve, absence of the left abducens nerve, and atrophy of the right half of the tongue, confirming hypoglossal involvement. This case underscores the importance of early recognition and detailed MRI evaluation to detect atypical cranial nerve anomalies in children with Moebius syndrome.

CureusVol. 17(11)
All India Institute of Medical Sciences, Deoghar (IN)
Openalex Percentile: Top 43%
Pectus Deformity Diagnosis and Treatment
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