Methotrexate toxicity and intolerance in paediatric inflammatory bowel disease: A retrospective cohort study
MTX-induced AEs are common but rarely severe in paediatric IBD. Male sex, MTX dosage, and oral administration significantly influence the risk of MTX-induced AEs.
Authors
- Nanne K.H. de Boer (ORCID: https://orcid.org/0000-0001-8357-9887)
- M Bulatović-Ćalasan
- Johan Van Limbergen (ORCID: https://orcid.org/0000-0001-5822-4371)
- Róbert de Jonge (ORCID: https://orcid.org/0000-0002-3454-0094)
- Eduard A. Struys (ORCID: https://orcid.org/0009-0002-8437-4108)
- Eva Vermeer (ORCID: https://orcid.org/0009-0009-4335-0100)
- Tim G. J. de Meij
- Eric Soetens
Institutions
- University Medical Center Utrecht (NL)
- Emma Kinderziekenhuis (NL)
- Amsterdam Neuroscience (NL)
- Amsterdam Institute for Addiction Research (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Journal of Pediatric Gastroenterology and Nutrition
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1002/jpn3.70300
- Citations
- 1
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82