Long‐term disease control of disseminated superficial actinic porokeratosis (DSAP) with simvastatin 2%/ cholesterol 2% cream

SC cream is a promising long-term, targeted treatment for DSAP, offering sustained efficacy, good tolerability, and improved QoL. The individual tapering from daily use to a proactive approach twice a week may be a key factor for disease control and may become an important component of skin tumor prevention in this specific patient population.

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Publication Details

Journal
JDDG Journal der Deutschen Dermatologischen Gesellschaft
Published
2025-11-29
DOI
https://doi.org/10.1111/ddg.15950
Primary Topic
Genetic and rare skin diseases.
Type
article
Field-Weighted Citation Impact
0.00
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article

Long‐term disease control of disseminated superficial actinic porokeratosis (DSAP) with simvastatin 2%/ cholesterol 2% cream

Berenice M. Lang, Gregor Ojak, Joanna Wegner, Petra Staubach et al.
JDDG Journal der Deutschen Dermatologischen Gesellschaft
Genetic and rare skin diseases.
article

Long‐term disease control of disseminated superficial actinic porokeratosis (DSAP) with simvastatin 2%/ cholesterol 2% cream

Berenice M. Lang, Gregor Ojak, Joanna Wegner, Petra Staubach, Stephan Grabbe, Caroline Mann, Mandy Crummenauer
article en

Abstract

SC cream is a promising long-term, targeted treatment for DSAP, offering sustained efficacy, good tolerability, and improved QoL. The individual tapering from daily use to a proactive approach twice a week may be a key factor for disease control and may become an important component of skin tumor prevention in this specific patient population.

JDDG Journal der Deutschen Dermatologischen Gesellschaft
Goethe University Frankfurt (DE), University of Kaiserslautern (DE), University of Applied Sciences Mainz (DE), Photonik-Zentrum Kaiserslautern (DE), University Hospital Frankfurt (DE), Frankfurt University of Applied Sciences (DE), University of Applied Sciences Kaiserslautern (DE)
Openalex Percentile: Top 61%
Genetic and rare skin diseases.
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