An absorbed dose‐based source strength determination for diffusing alpha‐emitters radiation therapy (DaRT) brachytherapy seeds – Proof of concept

This work investigated and reported a large dependence of absorbed dose to water on desorption of <sup>224</sup>Ra progeny. An absorbed dose-based source strength specification was proposed with a preliminary design of the apparatus. Using MC methods, the proposed instrument was deemed suitable for source strength measurements with a high sensitivity to changes in the DaRT seed construction.

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Journal
Medical Physics
Published
2025-11-29
DOI
https://doi.org/10.1002/mp.70167
Primary Topic
Advanced Radiotherapy Techniques
Type
article
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article

An absorbed dose‐based source strength determination for diffusing alpha‐emitters radiation therapy (DaRT) brachytherapy seeds – Proof of concept

Ahtesham Ullah Khan, Jeffrey L. Radtke, Larry A. DeWerd, Sean Jollota
Medical Physics
Advanced Radiotherapy Techniques
article

An absorbed dose‐based source strength determination for diffusing alpha‐emitters radiation therapy (DaRT) brachytherapy seeds – Proof of concept

Ahtesham Ullah Khan, Jeffrey L. Radtke, Larry A. DeWerd, Sean Jollota
article en

Abstract

This work investigated and reported a large dependence of absorbed dose to water on desorption of <sup>224</sup>Ra progeny. An absorbed dose-based source strength specification was proposed with a preliminary design of the apparatus. Using MC methods, the proposed instrument was deemed suitable for source strength measurements with a high sensitivity to changes in the DaRT seed construction.

Medical PhysicsVol. 52(12)
University of Wisconsin–Madison (US)
Openalex Percentile: Top 53%
Advanced Radiotherapy Techniques
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An absorbed dose‐based source strength determination for diffusing alpha‐emitters radiation therapy (DaRT) brachytherapy seeds – Proof of concept — Ahtesham Ullah Khan, Jeffrey L. Radtke, et al. · Medical Physics (2025) | TGRS Research Map | TGRS