Characteristics and quality of life of nine-year survivors with metastatic melanoma treated with pembrolizumab beyond second-line therapy
Pembrolizumab induced long-term survival in a real-world pretreated melanoma cohort. Despite persisting symptoms in one third, QoL, when measured by standard instruments, was good for most survivors nearly a decade after treatment.
Authors
- Claus Garbe (ORCID: https://orcid.org/0000-0001-8530-780X)
- C. Berking
- Jochen Sven Utikal (ORCID: https://orcid.org/0000-0001-5316-0241)
- L. Zimmer
- Michael Erdmann (ORCID: https://orcid.org/0000-0001-7136-6489)
- A. Forschner
- R. Gutzmer
- Cindy Franklin (ORCID: https://orcid.org/0000-0001-9142-5423)
- Armin Bender
- A. Hauschild
- Katharina C. Kähler (ORCID: https://orcid.org/0000-0001-9953-0893)
- M. Weichenthal
- Friedegund Meier (ORCID: https://orcid.org/0000-0003-4340-9706)
- D. Schadendorf
- Ina Holst
- Martin Gschnell
- Anca Sindrilaru (ORCID: https://orcid.org/0000-0002-1691-0047)
- Susanne Dugas‐Breit (ORCID: https://orcid.org/0000-0002-1339-6353)
- Lucie Heinzerling (ORCID: https://orcid.org/0000-0001-5718-3643)
- Peter Mohr
- J.C. Hassel
- Annika Brekner
Institutions
- Philipps University of Marburg (DE)
- University of Cologne (DE)
- Johannes Gutenberg University Mainz (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- National Center for Tumor Diseases (DE)
- University Hospital Schleswig-Holstein (DE)
- Essen University Hospital (DE)
- Elbe Kliniken Stade-Buxtehude (DE)
- Comprehensive Cancer Center Erlangen (DE)
- University Hospital Cologne (DE)
- University Hospital Ulm (DE)
- University Hospital Carl Gustav Carus (DE)
- Johannes Wesling Klinikum Minden (DE)
- University of Tübingen (DE)
- Ruhr University Bochum (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- European Journal of Cancer
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1016/j.ejca.2025.116149
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05