Andrographolide Induces ROS-dependent Apoptosis and Suppresses STAT3 Phosphorylation in Primary Effusion Lymphoma Cells
AG exerts anti-tumor effects against PEL by inducing ROS-dependent apoptosis and suppressing STAT3 signaling. These findings suggest that AG may serve as a promising therapeutic agent for PEL.
Authors
- Kulthida Vaeteewoottacharn (ORCID: https://orcid.org/0000-0001-6557-9680)
- Phorutai Pearngam (ORCID: https://orcid.org/0000-0003-0953-7851)
- Seiji Okada (ORCID: https://orcid.org/0000-0003-3124-5206)
- Rungnapha Saeeng (ORCID: https://orcid.org/0000-0003-2437-2231)
- Piyanard Boonnate (ORCID: https://orcid.org/0000-0001-6275-3583)
- Gunya Sittithumcharee (ORCID: https://orcid.org/0000-0001-5855-5285)
- Itnarin Mongkon
- Ryusho Kariya
- Krittamate Saisuwan (ORCID: https://orcid.org/0009-0009-0928-2909)
- Nutsara Settha
Institutions
- Burapha University (TH)
- Siriraj Hospital (TH)
- Khon Kaen University (TH)
- Mahidol University (TH)
- Kobe Gakuin University (JP)
- Chulabhorn Research Institute (TH)
- Kumamoto University (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-11-29
- DOI
- https://doi.org/10.21873/anticanres.17869
- Primary Topic
- Andrographolide Research and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00