Determining Candidate D-dimer Thresholds for Lower-extremity Ultrasound in Monitoring Deep Vein Thrombosis in Patients With Gastric Cancer Receiving Ramucirumab

This exploratory study suggests that a D-dimer level ≥4.4 μg/ml may serve as a candidate indicator for determining the need for lower-extremity ultrasonography in RAM-treated patients with gastric cancer. However, the small number of VTE events and the selective nature of the ROC cohort limit the generalizability. Validation in larger studies is needed.