Differences in pulmonary exacerbation risks among CF subpopulations
Prior-year PEx frequency (treated by any route) was strongly associated with future PEx risk independent of modulator use. Although ETI reduces PEx rates, agents intended to further reduce rates can be studied in pwCF receiving ETI having experienced higher numbers of prior-year PEx.
Authors
- Michael W. Konstan (ORCID: https://orcid.org/0000-0002-0557-7277)
- Donald R. VanDevanter (ORCID: https://orcid.org/0000-0002-5727-8164)
- Colin O’Rourke (ORCID: https://orcid.org/0000-0002-7913-1323)
- N. Hamblett
- John P. Clancy (ORCID: https://orcid.org/0000-0002-9695-097X)
Institutions
- Center for Infectious Disease Research (US)
- Cystic Fibrosis Foundation (US)
- Seattle Children's Hospital (US)
- Rainbow Babies & Children's Hospital (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Journal of Cystic Fibrosis
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1016/j.jcf.2025.11.010
- Citations
- 1
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Cystic Fibrosis Foundation