Ivarmacitinib ointment in treatment of adults with mild-to-moderate atopic dermatitis: phase III of a randomized double-blind placebo-controlled phase II/III clinical trial
Twice-daily ivarmacitinib ointment (0.5% or 1%) produced rapid, durable and well-tolerated improvements in the signs, symptoms and itch experienced by adults with mild-to-moderate AD, supporting its potential as a safe, steroid-sparing topical therapy.
Authors
- Chao Ji (ORCID: https://orcid.org/0000-0002-2282-3505)
- Guohong Hu (ORCID: https://orcid.org/0000-0002-2980-5166)
- Jinhua Xu (ORCID: https://orcid.org/0000-0002-2725-4903)
- Duoqin Wang (ORCID: https://orcid.org/0000-0001-9395-5401)
- Siping Zhang (ORCID: https://orcid.org/0000-0001-6230-5107)
- Rixin Chen (ORCID: https://orcid.org/0000-0002-2507-0609)
- Qingchun Diao
- Jianyun Lu (ORCID: https://orcid.org/0000-0001-7187-8871)
- Rupeng Wang (ORCID: https://orcid.org/0000-0002-4759-5852)
- Xiaohua Tao (ORCID: https://orcid.org/0000-0003-3527-2914)
- Rong Xiao (ORCID: https://orcid.org/0000-0002-6214-8057)
- Jiyuan Wu (ORCID: https://orcid.org/0000-0002-3129-502X)
- Fuqiu Li (ORCID: https://orcid.org/0000-0002-2175-5782)
- Liming Wu (ORCID: https://orcid.org/0000-0002-5738-0468)
- Xiaoman Gao
- Jing Li (ORCID: https://orcid.org/0000-0001-9392-6600)
- Linfeng Li (ORCID: https://orcid.org/0000-0002-8736-6464)
- Hui Wang (ORCID: https://orcid.org/0009-0005-5759-3593)
- Jinyan Wang (ORCID: https://orcid.org/0000-0001-7440-4073)
- Qing Guo (ORCID: https://orcid.org/0000-0002-4148-7041)
- Xiuping Han (ORCID: https://orcid.org/0000-0003-1228-0436)
- Hao Cheng (ORCID: https://orcid.org/0000-0001-5089-6747)
- Zhiming Li (ORCID: https://orcid.org/0000-0001-5589-1136)
- Jiande Han
- Yumei Li (ORCID: https://orcid.org/0009-0002-0117-7003)
- Sujun Liu (ORCID: https://orcid.org/0000-0002-3950-4666)
- Zhiqiang Song (ORCID: https://orcid.org/0000-0003-4297-9061)
- Pan Liu (ORCID: https://orcid.org/0000-0002-5577-3794)
- Yangfeng Ding (ORCID: https://orcid.org/0000-0002-0287-2190)
- Xunyi Dai
Institutions
- Jiangsu University (CN)
- Fujian Medical University (CN)
- Southwest General Health Center (US)
- Central South University (CN)
- Sun Yat-sen University (CN)
- Capital Medical University (CN)
- Sichuan University (CN)
- Fudan University (CN)
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Sir Run Run Shaw Hospital (CN)
- West China Hospital of Sichuan University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Affiliated Hospital of Jiangsu University (CN)
- Jiangxi Chest Hospital (CN)
- Nanyang Institute of Technology (CN)
- Xinqiao Hospital (CN)
- Beijing Hospital (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Third People's Hospital of Hangzhou (CN)
- Wuxi No.2 People's Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Anhui Provincial Hospital (CN)
- Zhejiang Provincial People's Hospital (CN)
- Southwest Hospital (CN)
- Wuhan Third Hospital (CN)
- Second Affiliated Hospital of Jilin University (CN)
- The First People's Hospital of Guiyang (CN)
- Beijing Friendship Hospital (CN)
- Jiangsu Hengrui Medicine (China) (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Second Xiangya Hospital of Central South University (CN)
- Shanghai Skin Disease Hospital (CN)
- Third Xiangya Hospital (CN)
- Huashan Hospital (CN)
- First People's Hospital of Chongqing (CN)
- Zhejiang University (CN)
- China Medical University (CN)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1093/bjd/ljaf482
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00