Platelet components with persistent aggregates are more activated, which do not change following pre‐transfusion filtration: The <scp>BEST</scp> collaborative study
Platelets in PCs with aggregates are markedly activated, and filtration does not change their phenotype. PCs containing many, large aggregates should be discarded, but those with fewer, small aggregates (aggregate score of 6 or less) could be retained.
Authors
- Marc Cloutier (ORCID: https://orcid.org/0000-0002-0598-8754)
- Moritz Stolla (ORCID: https://orcid.org/0000-0002-2866-1674)
- Teresa Jimenéz‐Marco (ORCID: https://orcid.org/0000-0001-9631-6541)
- Denese C. Marks (ORCID: https://orcid.org/0000-0002-3674-6934)
- Pieter F. van der Meer (ORCID: https://orcid.org/0000-0002-2093-3604)
- Susanne Marschner (ORCID: https://orcid.org/0000-0002-7862-6201)
- Thomas R. Klei (ORCID: https://orcid.org/0000-0002-2864-4073)
- Lacey Johnson (ORCID: https://orcid.org/0000-0003-3303-4437)
- Fabrice Cognasse (ORCID: https://orcid.org/0000-0001-8041-928X)
- Chloë E. George (ORCID: https://orcid.org/0000-0003-3857-378X)
Institutions
- The University of Sydney (AU)
- NHS Blood and Transplant (GB)
- Héma-Québec (CA)
- Australian Red Cross Lifeblood (AU)
- Bloodworks Northwest (US)
- Sanquin (NL)
- Health Research Institute of the Balearic Islands (ES)
- Vitalant (US)
- Établissement Français du Sang (FR)
- Universitat de les Illes Balears (ES)
Publication Details
- Journal
- Transfusion
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1111/trf.18478
- Citations
- 1
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.77