Rat bite fever presenting as localized cellulitis: The first documented presumptive case from Nepal and a call for clinical awareness

This case represents the first documented presumptive case of Spirillum minus RBF in Nepal, which presented atypically. It underscores the importance of clinical suspicion over microbiological confirmation in diagnosing RBF and emphasizes considering RBF in the differential diagnosis of febrile patients with cellulitis and a history of rodent exposure. Early initiation of empiric antibiotic therapy and timely surgical intervention can prevent serious complications. This case highlights RBF as an under-recognized zoonotic disease in Nepal and the need for greater clinical awareness and strengthened public health measures focused on rodent control.

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Publication Details

Journal
IDCases
Published
2025-11-29
DOI
https://doi.org/10.1016/j.idcr.2025.e02440
Primary Topic
Rabies epidemiology and control
Type
article
Field-Weighted Citation Impact
0.00
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article

Rat bite fever presenting as localized cellulitis: The first documented presumptive case from Nepal and a call for clinical awareness

Kaushal Sharma, Suman Chaudhary, Shankar Adhikari
IDCases
Rabies epidemiology and control
article

Rat bite fever presenting as localized cellulitis: The first documented presumptive case from Nepal and a call for clinical awareness

Kaushal Sharma, Suman Chaudhary, Shankar Adhikari
article en

Abstract

This case represents the first documented presumptive case of Spirillum minus RBF in Nepal, which presented atypically. It underscores the importance of clinical suspicion over microbiological confirmation in diagnosing RBF and emphasizes considering RBF in the differential diagnosis of febrile patients with cellulitis and a history of rodent exposure. Early initiation of empiric antibiotic therapy and timely surgical intervention can prevent serious complications. This case highlights RBF as an under-recognized zoonotic disease in Nepal and the need for greater clinical awareness and strengthened public health measures focused on rodent control.

IDCasesVol. 43
Detroit Historical Society (US)
Openalex Percentile: Top 60%
Rabies epidemiology and control
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