Genomic evolution and epidemiological impact of SARS-CoV-2 omicron subvariants in Taiwan, 2023–2025
Taiwan experienced dynamic evolution of SARS-CoV-2 Omicron, dominated by JN.1 and its derivatives, which drove successive infection waves. Changes in national case definitions created substantial surveillance artifacts complicating interpretation of disease burden. Although national data reaffirm advanced age as the key risk factor for severe outcomes, these findings underscore the importance of targeted vaccination strategies and integrated surveillance systems capable of distinguishing the effects of viral evolution from policy-driven reporting changes.
Authors
- Song Lin (ORCID: https://orcid.org/0000-0003-0393-010X)
- Chao‐Ju Chen
- Ping‐Chang Lin (ORCID: https://orcid.org/0000-0002-0169-7765)
- Po‐Chih Chen (ORCID: https://orcid.org/0000-0003-1637-9329)
- Chun‐Hong Chen (ORCID: https://orcid.org/0000-0002-3028-5508)
- Jih‐Jin Tsai (ORCID: https://orcid.org/0000-0003-2226-8916)
- Yi-Ching Lin (ORCID: https://orcid.org/0000-0002-5166-1330)
- Li‐Teh Liu (ORCID: https://orcid.org/0000-0002-7993-7263)
- Chen-Hsuan Lin (ORCID: https://orcid.org/0009-0005-1656-7188)
- Ching‐Yi Tsai (ORCID: https://orcid.org/0000-0002-4062-1958)
Institutions
- Chung Hwa University of Medical Technology (TW)
- Kaohsiung Medical University (TW)
- National Health Research Institutes (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
Publication Details
- Journal
- Journal of Infection and Public Health
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1016/j.jiph.2025.103075
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.40