The prognostic value of tumor macroscopic morphology in colorectal cancer
We proposed a revised tumor macroscopic morphology classification system in CRC. The infiltrative type is associated with poorer clinical outcomes, characterized by increased cancer-associated fibroblast (CAF) infiltration and enhanced angiogenesis compared with other types. Importantly, when expanded to endoscopy and CT preoperatively, both endoscopic and radiological morphology can serve as preoperative predictors of DFS.
Authors
- Hsin‐Yi Lin (ORCID: https://orcid.org/0000-0002-1401-1603)
- Limei Guo (ORCID: https://orcid.org/0000-0003-0430-2914)
- Zimin Zhao
- Yao Ma (ORCID: https://orcid.org/0000-0002-5868-1166)
- Junwei Wang (ORCID: https://orcid.org/0000-0001-9764-9524)
- Xin Zhou (ORCID: https://orcid.org/0009-0003-8604-2323)
- Wei Fu (ORCID: https://orcid.org/0000-0003-4813-0421)
- Xiangchao Shi (ORCID: https://orcid.org/0009-0002-2666-7455)
Institutions
- Peking University (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1016/j.tranon.2025.102607
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00