Antigenic drift in SARS-CoV-2: diminished vaccine protection in pediatric populations against Omicron and its JN.1 subvariant
Our findings highlight the urgent need for updating pediatric vaccines to include antigens from circulating virus variants in order to increase immune protection and reduce susceptibility to infection and controlling community transmission.
Authors
- Georon Ferreira de Sousa (ORCID: https://orcid.org/0000-0001-8780-202X)
- João Renato Rebello Pinho (ORCID: https://orcid.org/0000-0003-3999-0489)
- Carla Torres Braconi (ORCID: https://orcid.org/0000-0002-5370-8980)
- Erika Donizette Candido (ORCID: https://orcid.org/0000-0002-9132-569X)
- Edison Luíz Durigon (ORCID: https://orcid.org/0000-0003-4898-6553)
- Vanesca de Souza Lino (ORCID: https://orcid.org/0000-0002-4613-5475)
- Ruth Dálety da Silva Brito
- Cristiane Moutinho Lagos de Melo (ORCID: https://orcid.org/0000-0002-8831-0163)
- Mário Gabriel Lopes Barboza (ORCID: https://orcid.org/0000-0002-1309-6182)
- Danielle Bruna Leal Oliveira (ORCID: https://orcid.org/0000-0002-0534-0886)
- Mayanna Moreira Costa Fogaça
- Milena Silva Souza (ORCID: https://orcid.org/0000-0002-2556-9178)
- Jéssica Pires Farias (ORCID: https://orcid.org/0000-0001-5479-8175)
- Luís Carlos de Souza Ferreira (ORCID: https://orcid.org/0000-0002-4883-1693)
- Jaime Henrique Amorim (ORCID: https://orcid.org/0000-0002-0623-2879)
- A Santos (ORCID: https://orcid.org/0000-0002-9366-7124)
- Paloma Oliveira Vidal
Institutions
- Institut Pasteur (FR)
- Universidade de São Paulo (BR)
- Universidade Federal de Pernambuco (BR)
- Hospital Israelita Albert Einstein (BR)
- Universidade Federal do Oeste da Bahia (BR)
- Institute of Biomedical Science (GB)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Expert Review of Vaccines
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1080/14760584.2025.2597455
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00