Dietary antioxidants and CKM–depression comorbidity: a primary analysis with a secondary evaluation of all-cause mortality using six machine learning algorithms
Specific anthocyanidins were cross-sectionally associated with lower CKM-depression comorbidity and, for petunidin and total anthocyanidins, with lower mortality hazard. Given the observational design and potential residual confounding, these findings should be interpreted as associations rather than causal or protective effects.
Authors
- Juncang Wu (ORCID: https://orcid.org/0000-0002-2632-5757)
- Xun He (ORCID: https://orcid.org/0000-0002-2525-9102)
- Qiuwan Liu
- Jie Hu (ORCID: https://orcid.org/0000-0003-2940-6525)
- Yu Wang (ORCID: https://orcid.org/0000-0001-5107-8770)
- Yueyu Zhang (ORCID: https://orcid.org/0000-0001-8460-268X)
- Kangrui Zhang (ORCID: https://orcid.org/0000-0002-9810-0776)
- Sheng Wang (ORCID: https://orcid.org/0000-0003-2696-2171)
- Hongwei Liu (ORCID: https://orcid.org/0000-0003-4690-4438)
- Xinyi Chen (ORCID: https://orcid.org/0009-0002-4912-8905)
- Yi Tang
- Z D Yue
- Zhengfei Ye
Institutions
- Shanxi Medical University (CN)
- Anhui Medical University (CN)
- Bozhou People's Hospital (CN)
- Anhui Provincial Hospital (CN)
- Third People's Hospital of Hefei (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s40001-025-03524-0
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00